Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methamphetamine SCHEMBL8534227 | 0.84 | TAAR1 (0.72) | TAAR1SLC18A2SIGMAR1KMT2ATRPA1 | |
| Levmetamfetamine SCHEMBL29878484 | 0.84 | TAAR1 (0.72) | TAAR1SLC18A2SIGMAR1KMT2ATRPA1 | |
| SCHEMBL178552 | 0.83 | TAAR1 (0.63) | TAAR1SLC18A2SIGMAR1SLC6A4TRPA1 | |
| SCHEMBL8976958 | 0.83 | TAAR1 (0.63) | TAAR1SLC18A2SIGMAR1SLC6A4TRPA1 | |
| Hydrochloric Acid SCHEMBL23524437 | 0.82 | TAAR1 (0.61) | TAAR1SLC18A2SIGMAR1SLC6A4TRPA1 | |
| SCHEMBL28833141 | 0.79 | TRPA1 (0.58) | KMT2AMAPK1PPARGPPARATRPA1 | |
| Mucic Acid SCHEMBL6466756 | 0.78 | TAAR1 (0.68) | TAAR1SLC18A2SIGMAR1KMT2ATRPA1 | |
| SCHEMBL805199 | 0.76 | ALDH1A1 (0.56) | KMT2AMAPK1PPARGTRPA1CPA1 | |
| SCHEMBL4608578 | 0.76 | ALDH1A1 (0.56) | KMT2AMAPK1PPARGTRPA1CPA1 | |
| SCHEMBL4608581 | 0.76 | ALDH1A1 (0.56) | KMT2AMAPK1PPARGTRPA1CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008292-A | Pesticidal method | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1991-04-16 | — | — | US | disclosed |
| US-4960797-A | Improving mood element, stimulating sexual activity of aged people; free of side effects | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1990-10-02 | — | — | US | disclosed |
| EP-0186680-B1 | PHENYLISOPROPYLAMINE DERIVATIVE AND ITS PREPARATION | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-03-30 | — | — | EP | disclosed |