Sugi Predict

Sugi Predict / Compounds / SCHEMBL977940

SCHEMBL977940

SCHEMBL977940

CCCCc1c(-c2c(F)cc(F)cc2F)c(C)nc2ncnn12

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 1/20 0.41
▸ MAPK1 P28482 3/20 0.40
▸ GAA P10253 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ ALDH1A1 P00352 4/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ TSHR P16473 2/20 0.38
▸ POLB P06746 1/20 0.38
▸ ENPP1 P22413 1/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL974128 0.87 ATM (0.40) ATMMAPK1GAAHTTSMN1; SMN2
SCHEMBL976462 0.84 MAPK1 (0.40) MAPK1GAAALDH1A1KMT2ATSHR
SCHEMBL5090573 0.84 MAPK1 (0.43) MAPK1GAAALDH1A1KMT2ATSHR
SCHEMBL975017 0.81 MAPK1 (0.39) MAPK1HTTSMN1; SMN2ALDH1A1KMT2A
SCHEMBL5096432 0.79 ALDH1A1 (0.47) MAPK1GAAALDH1A1KMT2ATSHR
SCHEMBL974576 0.77 PDE2A (0.39) MAPK1ALDH1A1KMT2ATSHRPOLB
SCHEMBL5433238 0.77 ALDH1A1 (0.45) MAPK1GAAALDH1A1KMT2ATSHR
SCHEMBL5445684 0.77 MAPK1 (0.45) MAPK1GAAALDH1A1KMT2ATSHR
SCHEMBL5443361 0.77 MAPK1 (0.45) MAPK1GAAALDH1A1KMT2ATSHR
SCHEMBL14489594 0.77 MAPK1 (0.45) MAPK1ALDH1A1KMT2ATSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8974806-B2 Method for producing aqueous active substance compositions of active substances that are hardly soluble in water BASF AKTIENGESELLSCHAFT (DE) 2015-03-10 — — US disclosed
US-8741324-B2 Liquid pesticide compositions BASF SE (DE) 2014-06-03 — — US disclosed
US-8728504-B2 Process for solubilizing hydrophobic active ingredients in aqueous medium BASF SE (DE) 2014-05-20 — — US disclosed
EP-2676680-A1 Use of hydrophobin polypeptides as penetration enhancers BASF SE (DE) 2013-12-25 — — EP disclosed
US-8497230-B2 Solid crop protection agents containing polyalkoxylate, method for their production and use thereof BASF AKTIENGESELLSCHAFT (DE) 2013-07-30 — — US disclosed
US-20130123108-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER BASF SE (DE) 2013-05-16 — — US disclosed
EP-1763300-B1 USE OF ETHER GROUP-CONTAINING POLYMERS AS SOLUBILIZERS BASF SE (DE) 2013-05-15 — — EP disclosed
US-20110312497-A1 USE OF HYDROPHOBIN AS A SPREADING AGENT BASF SE (DE) 2011-12-22 — — US disclosed
US-20110195844-A1 PROCESS FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AQUEOUS MEDIUM BASF SE (DE) 2011-08-11 — — US disclosed
EP-2308460-A1 Composition comprising active agents and at least one nitrogen-containing hyper-branched polymer BASF SE (DE) 2011-04-13 — — EP disclosed
EP-1776010-A2 METHOD FOR PRODUCING AQUEOUS ACTIVE SUBSTANCE COMPOSITIONS OF ACTIVE SUBSTANCES THAT ARE HARDLY SOLUBLE IN WATER BASF AKTIENGESELLSCHAFT (DE) 2007-04-25 — — EP disclosed
EP-1773121-A1 LIQUID PESTICIDE COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2007-04-18 — — EP disclosed
EP-1756188-A1 AMPHIPHILIC POLYMER COMPOSITIONS AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2007-02-28 — — EP disclosed
WO-2006125647-A1 METHOD FOR DETERMINING RESIDUES IN PLASTICS BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 — — WO disclosed
WO-2006125644-A1 METHOD FOR DETERMINING PESTICIDE RESIDUES IN SOIL OR PLANT MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 — — WO disclosed
WO-2006087227-A2 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER BASF AKTIENGESELLSCHAFT (DE) 2006-08-24 — — WO disclosed
WO-2006084680-A1 POLYMER COMPOSITIONS AND THEIR USE IN THE PRODUCTION OF ACTIVE OR EFFECTIVE INGREDIENT COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2006-08-17 — — WO disclosed
WO-2006015791-A2 METHOD FOR PRODUCING AQUEOUS ACTIVE SUBSTANCE COMPOSITIONS OF ACTIVE SUBSTANCES THAT ARE HARDLY SOLUBLE IN WATER BASF AKTIENGESELLSCHAFT (DE) 2006-02-16 — — WO disclosed
WO-2006002984-A1 LIQUID PESTICIDE COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2006-01-12 — — WO disclosed
WO-2005121201-A1 AMPHIPHILIC POLYMER COMPOSITIONS AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2005-12-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110312497-A1 USE OF HYDROPHOBIN AS A SPREADING AGENT PFN1, DSTN, CHN2 ATM 4843/4885MAPK1 3589/4885GAA 395/4885
US-20110195844-A1 PROCESS FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AQUEOUS MEDIUM IDUA, PHOSPHO1, HDHD5 ATM 2207/4885MAPK1 477/4885GAA 316/4885
US-20130123108-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER NOS1, NOS3, NPSR1 ATM 1793/4885MAPK1 2382/4885GAA 1692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.