SCHEMBL974576

SCHEMBL974576

Cc1nc2ncnn2c(CC2CCCCC2)c1-c1c(F)cc(F)cc1F

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 14/20 0.39
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.36
ENPP1 P22413 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL977655 0.87 PDE2A (0.35) PDE2AALDH1A1POLBTSHRKMT2A
SCHEMBL5529006 0.82 KMT2A (0.36) PDE2AALDH1A1POLBTSHRKMT2A
SCHEMBL976565 0.81 PDE2A (0.43) PDE2AMAPK1
SCHEMBL5090573 0.80 MAPK1 (0.43) MAPK1ALDH1A1POLBTSHRKMT2A
SCHEMBL5090639 0.78 PDE2A (0.42) PDE2AMAPK1ALDH1A1
SCHEMBL977940 0.77 ATM (0.41) MAPK1ALDH1A1POLBTSHRKMT2A
SCHEMBL974907 0.76 MAPK1 (0.41) PDE2AMAPK1TSHRKMT2A
SCHEMBL976753 0.76 ALDH1A1 (0.44) PDE2AMAPK1ALDH1A1POLBTSHR
SCHEMBL976462 0.76 MAPK1 (0.40) PDE2AMAPK1ALDH1A1POLBTSHR
SCHEMBL5096432 0.75 ALDH1A1 (0.47) MAPK1ALDH1A1POLBTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8974806-B2 Method for producing aqueous active substance compositions of active substances that are hardly soluble in water BASF AKTIENGESELLSCHAFT (DE) 2015-03-10 US disclosed
US-8741324-B2 Liquid pesticide compositions BASF SE (DE) 2014-06-03 US disclosed
US-8728504-B2 Process for solubilizing hydrophobic active ingredients in aqueous medium BASF SE (DE) 2014-05-20 US disclosed
EP-2676680-A1 Use of hydrophobin polypeptides as penetration enhancers BASF SE (DE) 2013-12-25 EP disclosed
US-8497230-B2 Solid crop protection agents containing polyalkoxylate, method for their production and use thereof BASF AKTIENGESELLSCHAFT (DE) 2013-07-30 US disclosed
US-20130123108-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER BASF SE (DE) 2013-05-16 US disclosed
EP-1763300-B1 USE OF ETHER GROUP-CONTAINING POLYMERS AS SOLUBILIZERS BASF SE (DE) 2013-05-15 EP disclosed
US-20110312497-A1 USE OF HYDROPHOBIN AS A SPREADING AGENT BASF SE (DE) 2011-12-22 US disclosed
US-20110195844-A1 PROCESS FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AQUEOUS MEDIUM BASF SE (DE) 2011-08-11 US disclosed
EP-2308460-A1 Composition comprising active agents and at least one nitrogen-containing hyper-branched polymer BASF SE (DE) 2011-04-13 EP disclosed
EP-1756188-B1 AMPHIPHILIC POLYMER COMPOSITIONS AND THEIR USE BASF AG (DE) 2007-12-05 EP disclosed
WO-2007125041-A1 HYPERBRANCHED POLYESTERS WITH A LOW ACID NUMBER AND USE THEREOF BASF SE (DE) 2007-11-08 WO disclosed
WO-2007125028-A1 METHOD FOR SOLUBILISING HYDROPHOBIC ACTIVE SUBSTANCES IN AN AQUEOUS MEDIUM BASF SE (DE) 2007-11-08 WO disclosed
US-20070184983-A1 Liquid pesticide compositions BASF SE (DE) 2007-08-09 US disclosed
WO-2007048851-A1 SOLID CROP PROTECTION AGENTS CONTAINING POLYALKOXYLATE, METHOD FOR THEIR PRODUCTION AND USE THEREOF BASF SE (DE) 2007-05-03 WO disclosed
EP-1756188-A1 AMPHIPHILIC POLYMER COMPOSITIONS AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2007-02-28 EP disclosed
WO-2006125647-A1 METHOD FOR DETERMINING RESIDUES IN PLASTICS BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 WO disclosed
WO-2006125644-A1 METHOD FOR DETERMINING PESTICIDE RESIDUES IN SOIL OR PLANT MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 WO disclosed
WO-2006087227-A2 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER BASF AKTIENGESELLSCHAFT (DE) 2006-08-24 WO disclosed
WO-2005121201-A1 AMPHIPHILIC POLYMER COMPOSITIONS AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2005-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110312497-A1 USE OF HYDROPHOBIN AS A SPREADING AGENT PFN1, DSTN, CHN2 PDE2A 3375/4885MAPK1 3589/4885ALDH1A1 3404/4885
US-20110195844-A1 PROCESS FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AQUEOUS MEDIUM IDUA, PHOSPHO1, HDHD5 PDE2A 3057/4885MAPK1 477/4885ALDH1A1 3286/4885
US-20130123108-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER NOS1, NOS3, NPSR1 PDE2A 310/4885MAPK1 2382/4885ALDH1A1 2770/4885
US-20070184983-A1 Liquid pesticide compositions CBR3, BBC3, DDT PDE2A 2608/4885MAPK1 2845/4885ALDH1A1 2725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.