SCHEMBL9790052

SCHEMBL9790052

BrC(c1ccccc1)c1ccccc1.BrCC(Br)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.38
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
HTR2A P28223 3/20 0.37
TAAR1 Q96RJ0 2/20 0.37
DPP4 P27487 2/20 0.35
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
F2 P00734 1/20 0.35
HRH1 P35367 2/20 0.34
MTOR P42345 1/20 0.34
RAB9A P51151 1/20 0.34
GRM7 Q14831 1/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331173 0.93 TRPA1 (0.42) TRPA1CES2CES1HTR2ATAAR1
Benzene SCHEMBL27990256 0.86 TRPA1 (0.38) TRPA1CES2CES1HTR2ATAAR1
SCHEMBL67123 0.82 CES2 (0.50) TRPA1CES2CES1HTR2ATAAR1
SCHEMBL11305311 0.79 CHRNB2 (0.48) TAAR1ALDH1A1
SCHEMBL12880577 0.79 CES2 (0.48) TRPA1CES2CES1HTR2ATAAR1
SCHEMBL7640651 0.79 LMNA (0.31) LMNA
SCHEMBL29124544 0.74 ALDH1A1 (0.48) TRPA1TSHRALDH1A1RAB9ALMNA
SCHEMBL9452584 0.74 HTR2A (0.43) TRPA1CES2CES1HTR2ATAAR1
SCHEMBL19317396 0.74 CES2 (0.44) TRPA1CES2CES1HTR2ATAAR1
SCHEMBL22042211 0.74 HRH1 (0.46) TRPA1CES2CES1HTR2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075488-A Fungicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-24 US disclosed