Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 12/20 | 0.47 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819343 | 0.88 | RAB9A (0.49) | FDPSFDFT1MAPT | |
| SCHEMBL9819288 | 0.85 | FDPS (0.51) | FDPSFDFT1 | |
| SCHEMBL9819305 | 0.84 | FDPS (0.47) | FDPSFDFT1 | |
| SCHEMBL9819397 | 0.83 | PPARA (0.47) | FDPSFDFT1 | |
| SCHEMBL9819447 | 0.83 | PPARA (0.47) | FDPSFDFT1 | |
| SCHEMBL9819301 | 0.82 | FDPS (0.41) | FDPSFDFT1 | |
| SCHEMBL9790653 | 0.78 | TRPM8 (0.56) | FDPSFDFT1MAPTCA12CA1 | |
| SCHEMBL11401437 | 0.77 | FDPS (0.47) | FDPSFDFT1 | |
| SCHEMBL9819303 | 0.75 | FDPS (0.51) | FDPSMAPTCA12CA1MMP8 | |
| SCHEMBL9819210 | 0.70 | NPC1 (0.46) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282320-B1 | BISPHOSPHONIC ACID DERIVATIVES AND MEDICINES CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4973576-A | ANTIARTHRITIC AGENTS, TREATMENT OF HYPERCALCEMIA | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| EP-0282320-A1 | Bisphosphonic acid derivatives and medicines containing the same | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |