SCHEMBL11401437

SCHEMBL11401437

CC(C)c1cc(NC(P(=O)(O)O)P(=O)(O)O)no1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 10/20 0.47
SMN1; SMN2 Q16637 8/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
FDFT1 P37268 2/20 0.45
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9790653 0.81 TRPM8 (0.56) FDPSSMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL9819252 0.77 FDPS (0.47) FDPSFDFT1
SCHEMBL9819301 0.75 FDPS (0.41) FDPSRAB9AALDH1A1FDFT1
SCHEMBL9819343 0.74 RAB9A (0.49) FDPSSMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL9819210 0.72 NPC1 (0.46) FDPSNPC1RAB9ATSHR
SCHEMBL9819288 0.72 FDPS (0.51) FDPSSMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL9819305 0.71 FDPS (0.47) FDPSSMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL9819238 0.71 FDPS (0.57) FDPSSMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL9819397 0.70 PPARA (0.47) FDPSSMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL11645370 0.69 SMN1; SMN2 (0.61) SMN1; SMN2NPC1RAB9AALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55089293-A None JP disclosed
JP-S5589293-A BISPHOSPHONIC ACID COMPOUND AND HERBICIDE CONSISTING OF IT AS ACTIVE INGREDIENT NISSAN CHEM IND LTD 1980-07-05 JP disclosed