Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DOCK5 | Q9H7D0 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795652 | 0.84 | ADRB1 (0.40) | CMA1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL9795750 | 0.80 | ALOX5 (0.35) | MAPTALOX5BACE1 | |
| SCHEMBL9795597 | 0.77 | ALOX5 (0.58) | CMA1KMT2AMEN1MAPTALOX5 | |
| SCHEMBL9795754 | 0.76 | ALOX5 (0.54) | CMA1LMNAMAPTRAB9AALOX5 | |
| SCHEMBL9795641 | 0.74 | ALOX5 (0.60) | L3MBTL1MAPTALOX5 | |
| SCHEMBL9795608 | 0.72 | ALOX5 (0.40) | L3MBTL1LMNAALDH1A1MAPTALOX5 | |
| SCHEMBL9795696 | 0.72 | BPTF (0.35) | KMT2AMEN1ALDH1A1KDM4ERAB9A | |
| SCHEMBL9796089 | 0.71 | ALOX5 (0.45) | KMT2AMEN1CYP2C9ALDH1A1MAPT | |
| SCHEMBL9795578 | 0.69 | MMP13 (0.40) | CMA1KMT2AMEN1ALOX15ALOX5 | |
| SCHEMBL9795576 | 0.69 | ALOX5 (0.54) | CMA1KMT2AMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |