Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SDHB | P21912 | 3/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795870 | 1.00 | NOS2 (0.41) | NOS2LMNASMN1; SMN2APLNRKDM4E | |
| SCHEMBL1051087 | 0.78 | LMNA (0.52) | LMNASMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL7754155 | 0.71 | LMNA (0.45) | LMNASMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL13926087 | 0.69 | NOS2 (0.46) | NOS2LMNAAPLNRGRM4 | |
| SCHEMBL6296316 | 0.69 | LMNA (0.44) | LMNASMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL10519534 | 0.69 | NOS3 (0.50) | NOS2LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8035367 | 0.69 | NOS2 (0.64) | NOS2LMNASMN1; SMN2APLNRKDM4E | |
| SCHEMBL10452895 | 0.67 | BPTF (0.57) | NOS2LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6561352 | 0.67 | SMN1; SMN2 (0.78) | LMNASMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL76774 | 0.66 | SDHB (0.60) | LMNASMN1; SMN2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988704-A | Pyrimidine fungicides for plants | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0224339-B1 | PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING SAME AND AGRICULTURAL OR HORTICULTURAL FUNGICIDAL COMPOSITION CONTAINING SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-02 | — | — | EP | disclosed |
| US-4814338-A | ANILINO PYRIMIDINE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-03-21 | — | — | US | disclosed |
| EP-0224339-A2 | Pyrimidine derivative, process for preparing same and agricultural or horticultural fungicidal composition containing same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-06-03 | — | — | EP | disclosed |