Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799522 | 0.80 | TUBB4A (0.39) | L3MBTL1CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9799280 | 0.75 | SIGMAR1 (0.40) | NPC1CYP1A2CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL9799824 | 0.74 | NPC1 (0.35) | MEN1KMT2AL3MBTL1NPC1CYP1A2 | |
| SCHEMBL5915004 | 0.68 | SMN1; SMN2 (0.43) | L3MBTL1NPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5914943 | 0.68 | SMN1; SMN2 (0.43) | L3MBTL1NPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9799293 | 0.67 | FDPS (0.38) | L3MBTL1NPC1SIGMAR1KCNH2RAB9A | |
| SCHEMBL14796960 | 0.64 | GRM2 (0.44) | MEN1KMT2ACHRM2CHRM1HTR1A | |
| SCHEMBL4622787 | 0.64 | CHRM3 (0.42) | MEN1KMT2ANPC1CYP2C9CYP2C19 | |
| SCHEMBL3264636 | 0.64 | CHRM3 (0.42) | MEN1KMT2ANPC1CYP2C9CYP2C19 | |
| SCHEMBL1678550 | 0.63 | ADRA1A (0.46) | MEN1KMT2AL3MBTL1SIGMAR1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298703-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4946862-A | Thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| CN-1039245-A | A kind of novel thiophene derivatives and its preparation method | TANABE SEIYAKU CO (JP) | 1990-01-31 | — | — | CN | disclosed |
| EP-0298703-A1 | A thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-01-11 | — | — | EP | disclosed |