Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799280 | 0.88 | SIGMAR1 (0.40) | FDPSKCNH2NPC1AOC3SIGMAR1 | |
| SCHEMBL9799267 | 0.80 | CYP3A4 (0.46) | KCNH2SMN1; SMN2AOC3 | |
| SCHEMBL9834177 | 0.79 | MAPT (0.42) | FDPSMAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9799232 | 0.77 | OPRM1 (0.40) | KCNH2MAPTSMN1; SMN2AOC3L3MBTL1 | |
| SCHEMBL10423292 | 0.76 | KDM4E (0.41) | KCNH2MAPT | |
| SCHEMBL9799815 | 0.76 | L3MBTL1 (0.35) | FDPSKCNH2MAPTNPC1RAB9A | |
| SCHEMBL9830678 | 0.71 | RIPK1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL30082857 | 0.67 | TRPM8 (0.38) | MAPTRAB9ALMNATRPM8 | |
| SCHEMBL9799434 | 0.67 | MEN1 (0.38) | KCNH2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9831796 | 0.67 | NPC1 (0.35) | MAPTNPC1RAB9AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298703-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4946862-A | Thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0298703-A1 | A thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-01-11 | — | — | EP | disclosed |