SCHEMBL980286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10193340	0.84	CA12 (0.36)	KDM4EALDH1A1MAPTKMT2AMEN1
	SCHEMBL982663	0.77	NOTUM (0.52)	HTR6KDM4EALDH1A1HPGDTSHR
	SCHEMBL982376	0.72	ALDH1A1 (0.40)	HTR6KDM4EALDH1A1HPGDTSHR
	SCHEMBL984051	0.72	MKNK2 (0.41)	HTR6KDM4EALDH1A1HPGDTSHR
	SCHEMBL10095290	0.72	RAB9A (0.46)	HTR6KDM4EALDH1A1HPGDTSHR
	SCHEMBL7850213	0.71	HTR6 (0.49)	HTR6KDM4EALDH1A1HPGDTSHR
	SCHEMBL982072	0.71	MKNK2 (0.42)	HTR6KDM4EALDH1A1HPGDTSHR
	SCHEMBL16549277	0.70	AMY1A (0.42)	KDM4EALDH1A1HPGDRAB9AMAPT
	SCHEMBL2433501	0.69	ALDH1A1 (0.50)	HTR6KDM4EALDH1A1HPGDTSHR
	SCHEMBL980895	0.69	MAPT (0.48)	HTR6KDM4EALDH1A1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.