SCHEMBL980655

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL981395	0.90	PFKFB2 (0.42)	PFKFB2NSD2PFKFB1PFKFB3DOT1L
	SCHEMBL12105791	0.89	PFKFB2 (0.48)	EGLN2ACSS2PFKFB2NSD2PFKFB1
	SCHEMBL4791991	0.89	PFKFB2 (0.43)	PFKFB2NSD2PFKFB1PFKFB3DOT1L
	SCHEMBL13152257	0.86	ACSS2 (0.44)	EGLN2ACSS2MAPTTP53CA12
	SCHEMBL984456	0.85	PFKFB2 (0.41)	PFKFB2NSD2PFKFB1PFKFB3DOT1L
	SCHEMBL10096328	0.85	BCL2 (0.42)	EGLN2ACSS2PFKFB2NSD2PFKFB1
	SCHEMBL10096734	0.82	KMT2A (0.49)	PFKFB2NSD2PFKFB1PFKFB3DOT1L
	SCHEMBL10096239	0.82	MAPK1 (0.42)	PFKFB2NSD2PFKFB1PFKFB3DOT1L
	SCHEMBL10193528	0.81	KDM4E (0.39)	EGLN2PFKFB2NSD2PFKFB1PFKFB3
	SCHEMBL12950290	0.81	KDM4E (0.39)	PFKFB2NSD2PFKFB1PFKFB3DOT1L

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.