SCHEMBL980975

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12308224	0.95	GRIK2 (0.40)	GRIK2GRIK1HTTKDM4EMAPK1
	SCHEMBL10095963	0.91	GRIK2 (0.41)	GRIK2GRIK1HTTKDM4EMAPK1
	SCHEMBL980448	0.89	GRIK2 (0.38)	GRIK2GRIK1HTTKDM4EMAPK1
	SCHEMBL10193437	0.89	PER2 (0.38)	GRIK2GRIK1ALDH1A1PER2CRY1
	SCHEMBL13152337	0.86	GRIK2 (0.41)	GRIK2GRIK1HTTKDM4EMAPK1
	SCHEMBL983249	0.86	GRIK2 (0.45)	GRIK2GRIK1HTTKDM4EMAPK1
	SCHEMBL10095399	0.82	GRIK2 (0.45)	GRIK2GRIK1HTTKDM4EMAPK1
	SCHEMBL10095838	0.82	GRIK2 (0.45)	GRIK2GRIK1HTTKDM4EMAPK1
	SCHEMBL979539	0.81	GRIK2 (0.48)	GRIK2GRIK1HTTKDM4EMAPK1
	SCHEMBL10097244	0.81	GRIK2 (0.50)	GRIK2GRIK1HTTKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.