SCHEMBL4125062

SCHEMBL4125062

O=C1N(Br)C(=O)C(c2ccccc2)(c2ccccc2)N1Cl

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.33
PKM P14618 1/20 0.33
ALDH1A1 P00352 2/20 0.32
ELANE P08246 2/20 0.31
F2 P00734 1/20 0.31
PLG P00747 1/20 0.31
CTSG P08311 1/20 0.31
CMA1 P23946 1/20 0.31
CTRC Q99895 1/20 0.31
LMNA P02545 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
REN P00797 1/20 0.31
APP P05067 1/20 0.31
BACE1 P56817 1/20 0.31
BACE2 Q9Y5Z0 1/20 0.31
CYP2C19 P33261 3/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TSHR P16473 1/20 0.30
HTR1A P08908 1/20 0.30
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4732888 0.81 PKM (0.34) NPSR1PKMALDH1A1LMNAREN
SCHEMBL9818448 0.81 PKM (0.34) NPSR1PKMALDH1A1ELANEF2
SCHEMBL10629919 0.75 MITF (0.43) NPSR1ELANELMNATDP1BACE1
SCHEMBL5358251 0.74 NPSR1 (0.33) NPSR1PKMALDH1A1ELANEF2
SCHEMBL10636162 0.70 ELANE (0.40) NPSR1ALDH1A1ELANEF2PLG
SCHEMBL763669 0.67 PKM (0.38) PKMALDH1A1ELANEF2PLG
SCHEMBL5075817 0.67 MMP2 (0.39) NPSR1PKMALDH1A1LMNATDP1
SCHEMBL10632046 0.67 ALDH1A1 (0.39) PKMALDH1A1ELANELMNAREN
SCHEMBL11335481 0.66 LMNA (0.58) NPSR1ELANELMNATDP1BACE1
SCHEMBL10636113 0.63 ELANE (0.36) PKMELANEF2CTSGCMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080299161-A1 Solid Biocide Composition and Sealed Biocide Article SANDERSON WILLIAM D 2008-12-04 US claimed
EP-1968380-A2 SOLID BIOCIDE COMPOSITION AND SEALED BIOCIDE ARTICLE Sanderson, William D. (US) 2008-09-17 EP claimed
WO-2007078838-A2 SOLID BIOCIDE COMPOSITION AND SEALED BIOCIDE ARTICLE SANDERSON WILLIAM D (US) 2007-07-12 WO claimed
EP-0698080-A4 LAVATORY CLEANING BLOCK BLOCK DRUG CO (US) 1998-07-29 EP claimed
US-5763376-A Lavatory cleaning block BLOCK DRUG COMPANY, INC. (US) 1998-06-09 US claimed
US-5578559-A Lavatory cleaning block BLOCK DRUG COMPANY, INC. (US) 1996-11-26 US claimed
EP-0698080-A1 LAVATORY CLEANING BLOCK BLOCK DRUG COMPANY INC. (US) 1996-02-28 EP claimed
WO-1994026863-A1 LAVATORY CLEANING BLOCK BLOCK DRUG COMPANY, INC. (US) 1994-11-24 WO claimed
US-9580896-B2 Apparatus and method for prolonged active agent in aqueous systems HOPKINS JOHN DAVID (US) 2017-02-28 US disclosed
US-20160002904-A1 APPARATUS AND METHOD FOR PROLONGED ACTIVE AGENT DELIVERY IN AQUEOUS SYSTEMS HOPKINS JOHN DAVID (US) 2016-01-07 US disclosed
US-20090232903-A1 BIOCIDE COMPOSITIONS SANDERSON WILLIAM D 2009-09-17 US disclosed
US-20080299161-A1 Solid Biocide Composition and Sealed Biocide Article SANDERSON WILLIAM D 2008-12-04 US disclosed
US-20080209621-A1 FLUSH VALVE TILSON ALEXANDER Q 2008-09-04 US disclosed
US-7208745-B2 Radiation image conversion panel KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-04-24 US disclosed
EP-0698080-A1 LAVATORY CLEANING BLOCK BLOCK DRUG COMPANY INC. (US) 1996-02-28 EP disclosed
US-5395546-A Halogenated hydantoin and aluminum hydroxide with mold release lubricant BLOCK DRUG COMPANY, INC. (US) 1995-03-07 US disclosed
EP-0503751-B1 Lavatory cleaning block BLOCK DRUG CO (US) 1994-11-30 EP disclosed
WO-1994026863-A1 LAVATORY CLEANING BLOCK BLOCK DRUG COMPANY, INC. (US) 1994-11-24 WO disclosed
US-5178787-A Toilets; time-release agents BLOCK DRUG COMPANY, INC. (US) 1993-01-12 US disclosed
EP-0503751-A1 Lavatory cleaning block BLOCK DRUG COMPANY INC. (US) 1992-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090232903-A1 BIOCIDE COMPOSITIONS CAT, BLVRB, BLK NPSR1 3969/4885PKM 4768/4885ALDH1A1 2096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.