Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819007 | 0.85 | CTDSP1 (0.43) | ALDH1A1LMNAKDM4EMAPTOPRD1 | |
| SCHEMBL9818778 | 0.80 | CYP2D6 (0.42) | CYP2D6KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL6255523 | 0.75 | MEN1 (0.56) | CYP2D6KMT2AMEN1OPRD1 | |
| SCHEMBL9818808 | 0.75 | CYP2D6 (0.53) | CYP2D6KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL9870100 | 0.72 | SLC6A4 (0.61) | — | |
| SCHEMBL9818773 | 0.69 | ALDH1A1 (0.61) | KMT2AALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL27528272 | 0.68 | KMT2A (0.44) | KMT2AALDH1A1KDM4E | |
| SCHEMBL9818776 | 0.68 | OPRD1 (0.52) | CYP2D6KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL2558628 | 0.66 | ALDH1A1 (0.47) | CYP2D6KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7260255 | 0.66 | ALDH1A1 (0.51) | CYP2D6KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983614-A | ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS | LES LABORATOIRES MERAM (FR) | 1991-01-08 | — | — | US | claimed |