Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.49 |
| ▸ | FDPS | P14324 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819288 | 0.91 | FDPS (0.51) | RAB9AFDPSHPGDNPC1SMN1; SMN2 | |
| SCHEMBL9819305 | 0.90 | FDPS (0.47) | RAB9AFDPSHPGDNPC1SMN1; SMN2 | |
| SCHEMBL9819397 | 0.89 | PPARA (0.47) | RAB9AFDPSHPGDNPC1SMN1; SMN2 | |
| SCHEMBL9819276 | 0.89 | PPARA (0.47) | RAB9AFDPSHPGDNPC1SMN1; SMN2 | |
| SCHEMBL9819447 | 0.89 | PPARA (0.47) | RAB9AFDPSHPGDNPC1SMN1; SMN2 | |
| SCHEMBL9819252 | 0.88 | FDPS (0.47) | FDPSMAPTFDFT1 | |
| SCHEMBL9819301 | 0.85 | FDPS (0.41) | RAB9AFDPSHPGDALDH1A1FDFT1 | |
| SCHEMBL9819303 | 0.78 | FDPS (0.51) | RAB9AFDPSNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9790653 | 0.76 | TRPM8 (0.56) | RAB9AFDPSNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11401437 | 0.74 | FDPS (0.47) | RAB9AFDPSNPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282320-B1 | BISPHOSPHONIC ACID DERIVATIVES AND MEDICINES CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| EP-0282320-A1 | Bisphosphonic acid derivatives and medicines containing the same | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |