Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819276 | 1.00 | PPARA (0.47) | PPARAFDPSRAB9AHPGDENPP2 | |
| SCHEMBL9819397 | 1.00 | PPARA (0.47) | PPARAFDPSRAB9AHPGDENPP2 | |
| SCHEMBL9819305 | 0.99 | FDPS (0.47) | PPARAFDPSRAB9AHPGDENPP2 | |
| SCHEMBL9819288 | 0.94 | FDPS (0.51) | PPARAFDPSRAB9AHPGDNPC1 | |
| SCHEMBL9819343 | 0.89 | RAB9A (0.49) | FDPSRAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL9819252 | 0.83 | FDPS (0.47) | FDPSFDFT1 | |
| SCHEMBL9819301 | 0.81 | FDPS (0.41) | FDPSRAB9AHPGDFDFT1ALDH1A1 | |
| SCHEMBL9790653 | 0.75 | TRPM8 (0.56) | FDPSRAB9ANPC1SMN1; SMN2FDFT1 | |
| SCHEMBL20377217 | 0.74 | FDPS (0.57) | FDPSENPP2S1PR2S1PR1S1PR3 | |
| SCHEMBL20377224 | 0.74 | FDPS (0.57) | FDPSENPP2S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282320-B1 | BISPHOSPHONIC ACID DERIVATIVES AND MEDICINES CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| EP-0282320-A1 | Bisphosphonic acid derivatives and medicines containing the same | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |