Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 15/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819343 | 0.85 | RAB9A (0.49) | FDPSHPGDRAB9AFDFT1ALDH1A1 | |
| SCHEMBL9819288 | 0.83 | FDPS (0.51) | FDPSHPGDRAB9AFDFT1ALDH1A1 | |
| SCHEMBL9819252 | 0.82 | FDPS (0.47) | FDPSFDFT1 | |
| SCHEMBL9819305 | 0.82 | FDPS (0.47) | FDPSHPGDRAB9AFDFT1ALDH1A1 | |
| SCHEMBL9819447 | 0.81 | PPARA (0.47) | FDPSHPGDRAB9AFDFT1ALDH1A1 | |
| SCHEMBL9819397 | 0.81 | PPARA (0.47) | FDPSHPGDRAB9AFDFT1ALDH1A1 | |
| SCHEMBL9819303 | 0.76 | FDPS (0.51) | FDPSRAB9AALDH1A1 | |
| SCHEMBL11401437 | 0.75 | FDPS (0.47) | FDPSRAB9AFDFT1ALDH1A1 | |
| SCHEMBL9790653 | 0.73 | TRPM8 (0.56) | FDPSRAB9AFDFT1ALDH1A1 | |
| SCHEMBL19772267 | 0.70 | RAB9A (0.40) | HPGDRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282320-B1 | BISPHOSPHONIC ACID DERIVATIVES AND MEDICINES CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| EP-0282320-A1 | Bisphosphonic acid derivatives and medicines containing the same | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |