Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.62 |
| ▸ | MEN1 | O00255 | 9/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3783627 | 0.90 | GPR35 (0.57) | KMT2AMEN1MAPK1MAPTLMNA | |
| SCHEMBL513878 | 0.85 | MEN1 (0.58) | KMT2AMEN1LMNAPDK1PDK2 | |
| SCHEMBL2091197 | 0.84 | ALDH1A1 (0.73) | MAPK1MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL3793403 | 0.84 | NLRP3 (0.53) | KMT2AMEN1MAPTPDK1PDK2 | |
| SCHEMBL3803167 | 0.83 | ALDH1A1 (0.77) | KMT2AMEN1MAPK1MAPTLMNA | |
| SCHEMBL2093882 | 0.82 | RAF1 (0.53) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL3612815 | 0.81 | MEN1 (0.67) | KMT2AMEN1MAPK1MAPTLMNA | |
| SCHEMBL30623497 | 0.81 | MEN1 (0.67) | KMT2AMEN1MAPK1MAPTLMNA | |
| SCHEMBL10710090 | 0.80 | MEN1 (0.79) | KMT2AMEN1MAPK1MAPTLMNA | |
| SCHEMBL2093283 | 0.80 | NLRP3 (0.60) | KMT2AMEN1MAPTLMNAPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221515-A1 | MONOSACCHARIDE DERIVATIVES | RANBAXY LABORATORIES INC. (IN) | 2009-09-03 | — | — | US | disclosed |
| US-20090221515-A1 | MONOSACCHARIDE DERIVATIVES | RANBAXY LABORATORIES INC. (IN) | 2009-09-03 | — | — | US | disclosed |
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| EP-0162669-A2 | Anticonvulsive compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |
| US-4138422-A | UREAS AND CARBAMATES FROM ISOCYANATES ON AN INERT SOLID GRANULAR MATERIAL | UNION CARBIDE CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221515-A1 | MONOSACCHARIDE DERIVATIVES | HLA-DRB1, MUC1, FUT5 | KMT2A 3928/4885MEN1 1520/4885MAPK1 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.