Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746321 | 0.81 | GAA (0.34) | THRB | |
| Hydrochloric Acid SCHEMBL6578636 | 0.78 | GAA (0.33) | THRB | |
| SCHEMBL10497056 | 0.72 | THRB (0.33) | THRB | |
| SCHEMBL10616785 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL10497670 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL10561846 | 0.68 | LMNA (0.32) | — | |
| Hydrochloric Acid SCHEMBL10718566 | 0.66 | ALDH1A1 (0.37) | — | |
| SCHEMBL1768795 | 0.62 | CYP3A4 (0.50) | — | |
| SCHEMBL11279678 | 0.61 | AR (0.41) | THRB | |
| SCHEMBL8767328 | 0.60 | GABRA2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245646-B1 | PROCESS FOR THE PREPARATION OF 1-ARYL-5-AMINO-PYRAZOLES | BAYER AG (DE) | 1991-09-11 | — | — | EP | disclosed |
| US-4824960-A | Preparation of 1-aryl-5-amino-pyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-25 | — | — | US | disclosed |