Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 9/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823368 | 0.87 | IKBKE (0.45) | TBK1IKBKERAB9AKDM4EGAA | |
| SCHEMBL9830987 | 0.81 | GAA (0.54) | RAB9AKDM4EGAANPC1ALDH1A1 | |
| SCHEMBL9831169 | 0.79 | RAB9A (0.36) | TBK1IKBKERAB9AKDM4EGAA | |
| SCHEMBL9823493 | 0.77 | KDM4E (0.46) | RAB9AKDM4EGAANPC1ALDH1A1 | |
| SCHEMBL9823799 | 0.76 | RAB9A (0.61) | RAB9AGAANPC1ALDH1A1HPGD | |
| SCHEMBL9823522 | 0.75 | RAB9A (0.55) | TBK1IKBKERAB9AKDM4EGAA | |
| SCHEMBL9830916 | 0.74 | RAB9A (0.45) | TBK1IKBKERAB9AKDM4EGAA | |
| SCHEMBL9832642 | 0.72 | SMN1; SMN2 (0.64) | RAB9AKDM4EGAANPC1ALDH1A1 | |
| SCHEMBL9831821 | 0.71 | MAPT (0.46) | RAB9AKDM4EGAANPC1ALDH1A1 | |
| SCHEMBL9830803 | 0.71 | ALDH1A1 (0.62) | RAB9AGAANPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262873-B1 | N-TETRAZOLYL THIAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4879295-A | ANTIALLERGENS | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |