Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829309 | 0.78 | NPC1 (0.43) | KDM4ENPC1HSD17B10ADORA3MEN1 | |
| SCHEMBL9831218 | 0.74 | RAB9A (0.42) | NPC1HSD17B10MAPK1KMT2AGAA | |
| SCHEMBL9828830 | 0.74 | ALDH1A1 (0.42) | KDM4ENPC1HSD17B10MAPK1ADORA3 | |
| SCHEMBL9829103 | 0.72 | ADORA3 (0.44) | KDM4EHSD17B10ADORA2AADORA3USP2 | |
| SCHEMBL9828154 | 0.71 | LMNA (0.46) | NPC1HSD17B10ADORA3MEN1KMT2A | |
| SCHEMBL9827533 | 0.69 | NPC1 (0.46) | KDM4ENPC1MAPK1ADORA3MEN1 | |
| SCHEMBL9828505 | 0.67 | ADORA3 (0.46) | KDM4EHSD17B10ADORA3MEN1KMT2A | |
| SCHEMBL9829223 | 0.64 | MEN1 (0.39) | KDM4ENPC1HSD17B10ADORA2AADORA3 | |
| SCHEMBL8999792 | 0.63 | KMO (0.59) | NPC1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL11964123 | 0.63 | RAB9A (0.53) | KDM4ENPC1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233804-B1 | MONOARYL-5-AS TRIAZINONES SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS | PIERRE FABRE MEDICAMENT (FR) | 1991-09-25 | — | — | EP | claimed |