Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827533 | 0.87 | NPC1 (0.46) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9829358 | 0.87 | CHEK1 (0.44) | LMNANPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL9828844 | 0.87 | CHEK1 (0.50) | LMNANPC1RAB9ASMN1; SMN2CHEK1 | |
| SCHEMBL9829354 | 0.86 | CHEK1 (0.43) | LMNANPC1RAB9ASMN1; SMN2CHEK1 | |
| SCHEMBL9831218 | 0.85 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2HSD17B10POLB | |
| SCHEMBL9828939 | 0.84 | MGAM (0.47) | LMNANPC1RAB9ACHEK1MEN1 | |
| SCHEMBL9829309 | 0.83 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL9828617 | 0.83 | ALDH1A1 (0.51) | LMNANPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL9829126 | 0.82 | CHEK1 (0.40) | LMNANPC1RAB9ASMN1; SMN2CHEK1 | |
| SCHEMBL9828505 | 0.82 | ADORA3 (0.46) | RAB9ATSHRHSD17B10MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233804-B1 | MONOARYL-5-AS TRIAZINONES SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS | PIERRE FABRE MEDICAMENT (FR) | 1991-09-25 | — | — | EP | claimed |