Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828830 | 0.89 | ALDH1A1 (0.42) | RAB9ANPC1ALDH1A1MAPTMITF | |
| SCHEMBL9829309 | 0.87 | NPC1 (0.43) | RAB9ANPC1ALDH1A1MAPTMITF | |
| SCHEMBL9828154 | 0.85 | LMNA (0.46) | RAB9ANPC1ALDH1A1MAPTMITF | |
| SCHEMBL9827533 | 0.83 | NPC1 (0.46) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9828333 | 0.74 | KDM4E (0.42) | RAB9ANPC1ALDH1A1MAPTMITF | |
| SCHEMBL9829223 | 0.72 | MEN1 (0.39) | RAB9ANPC1ALDH1A1SMN1; SMN2ACHE | |
| SCHEMBL9829358 | 0.72 | CHEK1 (0.44) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9828844 | 0.72 | CHEK1 (0.50) | RAB9ANPC1ALDH1A1MAPTMITF | |
| SCHEMBL9829103 | 0.72 | ADORA3 (0.44) | ALDH1A1MAPTL3MBTL1GAAHPGD | |
| SCHEMBL9829354 | 0.71 | CHEK1 (0.43) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233804-B1 | MONOARYL-5-AS TRIAZINONES SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS | PIERRE FABRE MEDICAMENT (FR) | 1991-09-25 | — | — | EP | claimed |