Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 7/20 | 0.61 |
| ▸ | HBB | P68871 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | EDNRA | P25101 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.46 |
| ▸ | POLG | P54098 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571583 | 0.87 | PNP (0.62) | PNPHBBBLMUSP2TSHR | |
| Hydrochloric Acid SCHEMBL11250267 | 0.86 | PNP (0.61) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL11724984 | 0.85 | PNP (0.60) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL10585595 | 0.85 | PNP (0.60) | PNPHBBBLMUSP2TSHR | |
| Acyclovir SCHEMBL40722 | 0.84 | PNP (0.58) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL11247946 | 0.83 | PNP (0.54) | PNPHBBBLMUSP2TSHR | |
| Acyclovir SCHEMBL4604274 | 0.83 | PNP (0.57) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL9233727 | 0.83 | PNP (0.57) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL23247753 | 0.82 | PNP (0.56) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL29767910 | 0.82 | PNP (0.56) | PNPHBBBLMUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200046715-A1 | Medicament for Treating Peripheral Neuropathies | HSIAO LILY (TW) | 2020-02-13 | — | — | US | disclosed |
| US-10471064-B2 | Medicament for treating peripheral neuropathies | Hsiao, Lily (TW) | 2019-11-12 | — | — | US | disclosed |
| US-20180193348-A1 | Medicament for Treating Peripheral Neuropathies | HSIAO LILY (TW) | 2018-07-12 | — | — | US | disclosed |
| US-20180193348-A1 | Medicament for Treating Peripheral Neuropathies | HSIAO LILY (TW) | 2018-07-12 | — | — | US | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| US-20170056408-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | YU HSIAO LILY (JP) | 2017-03-02 | — | — | US | disclosed |
| US-20170056408-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | YU HSIAO LILY (JP) | 2017-03-02 | — | — | US | disclosed |
| US-9526729-B2 | Medicament for treating peripheral neuropathies | Yu, Hsiao Lily (JP) | 2016-12-27 | — | — | US | disclosed |
| US-9526729-B2 | Medicament for treating peripheral neuropathies | Yu, Hsiao Lily (JP) | 2016-12-27 | — | — | US | disclosed |
| US-20150238493-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | YU HSIAO LILY (JP) | 2015-08-27 | — | — | US | disclosed |
| US-8853222-B2 | Treatment of herpes virus related diseases | EXLEY RAY W (US) | 2014-10-07 | — | — | US | disclosed |
| WO-2014145464-A1 | NUCLEOSIDE ANALOG SALTS WITH IMPROVED SOLUBILITY AND METHODS OF FORMING SAME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2014-09-18 | — | — | WO | disclosed |
| US-20140213600-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | HSIAO LILY (TW) | 2014-07-31 | — | — | US | disclosed |
| US-20140213600-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | HSIAO LILY (TW) | 2014-07-31 | — | — | US | disclosed |
| US-20110112117-A1 | TREATMENT OF HERPES VIRUS RELATED DISEASES | EXLEY RAY W | 2011-05-12 | — | — | US | disclosed |
| US-20110112117-A1 | TREATMENT OF HERPES VIRUS RELATED DISEASES | EXLEY RAY W | 2011-05-12 | — | — | US | disclosed |
| WO-2009111739-A2 | TREATMENT OF HERPES VIRUS RELATED DISEASES | EXLEY RAY W (US) | 2009-09-11 | — | — | WO | disclosed |
| EP-0217207-B1 | 2-AMINO PURINES SUBSTITUTED IN POSITIONS 6 AND 9, THEIR USE, MEDICAMENTS CONTAINING THESE PURINES AND PROCESSES FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | disclosed |
| EP-0400686-A1 | 2-Amino-9-[1,3bis-(isopropoxy)-propyl-2-oxymethyl]-purine, its utilization and medicaments containing it | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-12-05 | — | — | EP | disclosed |
| EP-0217207-A1 | 2-Amino purines substituted in positions 6 and 9, their use, medicaments containing these purines and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112117-A1 | TREATMENT OF HERPES VIRUS RELATED DISEASES | TPMT, METAP2, DNPEP | PNP 82/4885HBB 4014/4885BLM 4459/4885 |
| US-20140213600-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | PMP22, DPM1, SUCLG1 | PNP 2628/4885HBB 2084/4885BLM 2912/4885 |
| US-10471064-B2 | Medicament for treating peripheral neuropathies | NGF, TSLP, BDNF | PNP 719/4885HBB 4273/4885BLM 3727/4885 |
| US-20200046715-A1 | Medicament for Treating Peripheral Neuropathies | NGF, PMP22, BPGM | PNP 78/4885HBB 2477/4885BLM 3278/4885 |
| US-20180193348-A1 | Medicament for Treating Peripheral Neuropathies | NGF, TSLP, BDNF | PNP 719/4885HBB 4273/4885BLM 3727/4885 |
| US-20170056408-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | PMP22, SNCA, PARL | PNP 2845/4885HBB 1450/4885BLM 3073/4885 |
| US-20150238493-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | PMP22, SNCA, PARL | PNP 2845/4885HBB 1450/4885BLM 3073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.