SCHEMBL982857

SCHEMBL982857

O=C1CC=C(c2ccccc2)O1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 6/20 0.39
MAPT P10636 6/20 0.39
RAB9A P51151 3/20 0.39
HTT P42858 3/20 0.39
NPC1 O15118 2/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 5/20 0.37
MEN1 O00255 4/20 0.37
KDM4E B2RXH2 3/20 0.37
PKM P14618 2/20 0.37
ALOX12 P18054 2/20 0.37
POLB P06746 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CFTR P13569 1/20 0.37
GOPC Q9HD26 1/20 0.37
LMNA P02545 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7255969 0.96 CTRC (0.39) SMN1; SMN2MAPK1ALDH1A1MAPTRAB9A
SCHEMBL6603955 0.79 SMN1; SMN2 (0.37) SMN1; SMN2MAPK1ALDH1A1MAPTRAB9A
SCHEMBL11109234 0.79 MEN1 (0.36) ALDH1A1MAPTRAB9AHTTNPC1
SCHEMBL30537720 0.79 MAPT (0.36) SMN1; SMN2ALDH1A1MAPTRAB9ANPC1
SCHEMBL5732254 0.79 ALDH1A1 (0.36) SMN1; SMN2MAPK1ALDH1A1MAPTRAB9A
SCHEMBL31589994 0.77 GABRP (0.42) SMN1; SMN2ALDH1A1RAB9ANPC1KMT2A
SCHEMBL31590161 0.77 GABRP (0.42) SMN1; SMN2RAB9ANPC1
SCHEMBL21946058 0.75 HPGD (0.33) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL6137177 0.74 GAA (0.43) SMN1; SMN2ALDH1A1MAPTRAB9AHTT
SCHEMBL30537721 0.72 ALOX15 (0.37) KMT2AMEN1TDP1CTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115043810-B Method for preparing chiral hydrocarbon bond oxidation product by non-metal catalyzed asymmetric hydrocarbon bond oxidation 浙江大学 2024-04-19 CN disclosed
CN-115043810-A Method for preparing chiral carbon-hydrogen bond oxidation product by non-metal catalyzed asymmetric carbon-hydrogen bond oxidation 浙江大学 2022-09-13 CN disclosed
US-20110014504-A1 LITHIUM SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
US-7807691-B2 Substituted N-arylpyrrolidines as selective androgen receptor modulators ELI LILLY AND COMPANY (US) 2010-10-05 US disclosed
US-20080311478-A1 Lithium Secondary Battery MITSUBISHI CHEMICAL CORPORATION (JP) 2008-12-18 US disclosed
EP-1891038-B1 SUBSTITUTED N-ARYLPYRROLIDINES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS LILLY CO ELI (US) 2008-10-29 EP disclosed
US-20080176864-A1 Substituted N-Arylpyrrolidines as Selective Androgen Receptor Modulators ELI LILLY AND COMPANY 2008-07-24 US disclosed
EP-1891038-A2 SUBSTITUTED N-ARYLPYRROLIDINES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2008-02-27 EP disclosed
EP-1892789-A1 LITHIUM SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2008-02-27 EP disclosed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US disclosed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US disclosed
US-7193108-B2 Phenylpropionic acid derivatives AJINOMOTO CO., INC. (JP) 2007-03-20 US disclosed
US-7193108-B2 Phenylpropionic acid derivatives AJINOMOTO CO., INC. (JP) 2007-03-20 US disclosed
WO-2006124447-A2 SUBSTITUTED N-ARYLPYRROLIDINES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2006-11-23 WO disclosed
US-6956055-B2 Substituted γ-lactone compounds as NMDA-antagonists GRUNENTHAL GMBH (DE) 2005-10-18 US disclosed
WO-2003044007-A1 METHOD FOR THE PRODUCTION OF CHIRAL, NON-RACEMIC 5-SUBSTITUTED GAMMA-BUTYROLACTONES BAYER CROPSCIENCE AG (DE) 2003-05-30 WO disclosed
US-5328818-A Support with color couplers in emulsions in multilayer element FUJI PHOTO FILM CO., LTD. (JP) 1994-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 SMN1; SMN2 3654/4885MAPK1 1503/4885ALDH1A1 83/4885
US-20080176864-A1 Substituted N-Arylpyrrolidines as Selective Androgen Receptor Modulators AR, FSHR, SHBG SMN1; SMN2 376/4885MAPK1 774/4885ALDH1A1 1474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.