Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 3/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MGAM | O43451 | 2/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.45 |
| ▸ | SI | P14410 | 2/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828844 | 0.95 | CHEK1 (0.50) | ALDH1A1MAPTLMNASMN1; SMN2SRC | |
| SCHEMBL9828939 | 0.90 | MGAM (0.47) | ALDH1A1MAPTLMNASRCCHEK1 | |
| SCHEMBL9828154 | 0.83 | LMNA (0.46) | ALDH1A1MAPTLMNASMN1; SMN2CHEK1 | |
| SCHEMBL9829358 | 0.81 | CHEK1 (0.44) | ALDH1A1MAPTLMNASMN1; SMN2CHEK1 | |
| SCHEMBL9829354 | 0.80 | CHEK1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2CHEK1 | |
| SCHEMBL9828641 | 0.79 | MAPT (0.47) | ALDH1A1MAPTPOLBKMT2AKDM4E | |
| SCHEMBL9828830 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2SRCNPC1 | |
| SCHEMBL9829126 | 0.76 | CHEK1 (0.40) | MAPTLMNASMN1; SMN2CHEK1NPC1 | |
| SCHEMBL30531810 | 0.74 | SRC (0.85) | ALDH1A1MAPTLMNASMN1; SMN2SRC | |
| SCHEMBL9832501 | 0.71 | TLR8 (0.51) | ALDH1A1MAPTSMN1; SMN2CHEK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233804-B1 | MONOARYL-5-AS TRIAZINONES SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS | PIERRE FABRE MEDICAMENT (FR) | 1991-09-25 | — | — | EP | claimed |