Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828844 | 0.83 | CHEK1 (0.50) | MAPTRAB9AKDM4EKMT2APOLB | |
| SCHEMBL9828154 | 0.81 | LMNA (0.46) | MAPTRAB9AKMT2APOLBRXFP1 | |
| SCHEMBL9828939 | 0.80 | MGAM (0.47) | MAPTRAB9AKMT2APOLBRXFP1 | |
| SCHEMBL9828617 | 0.79 | ALDH1A1 (0.51) | MAPTRAB9AKDM4EKMT2APOLB | |
| SCHEMBL9829358 | 0.78 | CHEK1 (0.44) | MAPTRAB9AKMT2ARXFP1MEN1 | |
| SCHEMBL9829354 | 0.78 | CHEK1 (0.43) | MAPTRAB9AKMT2APOLBRXFP1 | |
| SCHEMBL9829126 | 0.74 | CHEK1 (0.40) | MAPTRAB9AKMT2APOLBRXFP1 | |
| SCHEMBL31172062 | 0.70 | ALDH1A1 (0.71) | MAPTRAB9AKMT2APOLBMEN1 | |
| SCHEMBL1849729 | 0.70 | RAB9A (0.62) | MAPTRAB9AKMT2AKCNH2RXFP1 | |
| SCHEMBL16411136 | 0.69 | ALDH1A1 (0.59) | MAPTKDM4EKMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233804-B1 | MONOARYL-5-AS TRIAZINONES SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS | PIERRE FABRE MEDICAMENT (FR) | 1991-09-25 | — | — | EP | claimed |