Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828617 | 0.95 | ALDH1A1 (0.51) | CHEK1GAAMGAMAMY1ASI | |
| SCHEMBL9828939 | 0.94 | MGAM (0.47) | CHEK1GAAMGAMAMY1ASI | |
| SCHEMBL9828154 | 0.87 | LMNA (0.46) | CHEK1NPC1RXFP1MAPTMEN1 | |
| SCHEMBL9829358 | 0.85 | CHEK1 (0.44) | CHEK1NPC1RXFP1MAPTMEN1 | |
| SCHEMBL9829354 | 0.84 | CHEK1 (0.43) | CHEK1NPC1RXFP1MAPTMEN1 | |
| SCHEMBL9828641 | 0.83 | MAPT (0.47) | RXFP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9829126 | 0.80 | CHEK1 (0.40) | CHEK1NPC1RXFP1MAPTMEN1 | |
| SCHEMBL9832501 | 0.75 | TLR8 (0.51) | CHEK1NPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9829232 | 0.74 | FYN (0.44) | CHEK1GAANPC1MAPTMEN1 | |
| SCHEMBL11097662 | 0.74 | ACHE (0.52) | GAAMGAMAMY1ASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233804-B1 | MONOARYL-5-AS TRIAZINONES SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS | PIERRE FABRE MEDICAMENT (FR) | 1991-09-25 | — | — | EP | claimed |