Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828844 | 0.94 | CHEK1 (0.50) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL9828617 | 0.90 | ALDH1A1 (0.51) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL9828154 | 0.84 | LMNA (0.46) | CHEK1NPC1ALDH1A1LMNARXFP1 | |
| SCHEMBL9829358 | 0.82 | CHEK1 (0.44) | CHEK1NPC1ALDH1A1LMNAHPGD | |
| SCHEMBL9829354 | 0.81 | CHEK1 (0.43) | CHEK1NPC1ALDH1A1LMNARXFP1 | |
| SCHEMBL9828641 | 0.80 | MAPT (0.47) | ALDH1A1HPGDRXFP1MAPTRAB9A | |
| SCHEMBL9829126 | 0.77 | CHEK1 (0.40) | CHEK1NPC1LMNARXFP1MAPT | |
| SCHEMBL29193525 | 0.73 | SRC (0.52) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL29050566 | 0.73 | SRC (0.77) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL9829223 | 0.73 | MEN1 (0.39) | NPC1ALDH1A1HPGDRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233804-B1 | MONOARYL-5-AS TRIAZINONES SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS | PIERRE FABRE MEDICAMENT (FR) | 1991-09-25 | — | — | EP | claimed |