Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SOD1 | P00441 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897520 | 0.94 | MAOA (0.47) | ALDH1A1MEN1RAB9AKMT2AKCNH2 | |
| SCHEMBL2170360 | 0.88 | CA12 (0.42) | ALDH1A1MEN1RAB9AKMT2AKDM4E | |
| SCHEMBL5536815 | 0.78 | ALDH3A1 (0.47) | MEN1RAB9AKMT2AKCNH2SOD1 | |
| SCHEMBL2511132 | 0.77 | CA12 (0.53) | ALDH1A1MEN1RAB9AKMT2AKCNH2 | |
| SCHEMBL187687 | 0.77 | ALDH3A1 (0.50) | ALDH1A1MEN1RAB9AKMT2AKCNH2 | |
| SCHEMBL6213159 | 0.77 | SOD1 (0.47) | ALDH1A1SOD1GRM5L3MBTL1TDP1 | |
| SCHEMBL10404569 | 0.77 | KCNH2 (0.46) | ALDH1A1MEN1RAB9AKMT2AKCNH2 | |
| SCHEMBL99544 | 0.77 | DAO (0.43) | RAB9ACYP1A2DAOMAOBAPP | |
| SCHEMBL514644 | 0.77 | L3MBTL1 (0.47) | KCNH2GRM5MAOBL3MBTL1 | |
| SCHEMBL6978990 | 0.77 | TDP1 (0.52) | ALDH1A1RAB9AMAOBAPPL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 500 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206809-A1 | PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY | VERA THERAPEUTICS INC (US) | 2021-07-08 | — | — | US | claimed |
| EP-3601237-A2 | PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY | Trucode Gene Repair, Inc. (US) | 2020-02-05 | — | — | EP | claimed |
| CN-110740994-A | Peptide Nucleic Acid (PNA) monomers with orthogonally protected ester moieties | 特鲁科德基因修复公司 | 2020-01-31 | — | — | CN | claimed |
| CN-105777640-B | Pyrazole cyclohexanediol ether compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-01-07 | — | — | CN | claimed |
| WO-2018175927-A2 | PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY | TRUCODE GENE REPAIR, INC. (US) | 2018-09-27 | — | — | WO | claimed |
| CN-104017001-B | A kind of method of chemosynthesis mosictin | DALIAN JOIN KING BIOLOGICAL CHEMICAL TECHNOLOGY CO., LTD. (CN) | 2016-01-13 | — | — | CN | claimed |
| EP-1512397-B1 | O-SUBSTITUTED HYDROXYARYL DERIVATIVES | INST MED MOLECULAR DESIGN INC (JP) | 2014-10-08 | — | — | EP | claimed |
| CN-104017001-A | Method of chemically synthesizing moxidectin | DALIAN JOIN KING BIOCHEM TECH CO LTD | 2014-09-03 | — | — | CN | claimed |
| EP-2248820-B1 | Universal supports for oligonucleotide synthesis | GLEN RES CORP (US) | 2014-01-08 | — | — | EP | claimed |
| EP-1506176-B1 | AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA SRL (IT) | 2013-04-24 | — | — | EP | claimed |
| US-4785010-A | AGING RESISTANCE OF HUMANS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | claimed |
| EP-0124067-B1 | 2-(AMINOALKYL)-PYRROLE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1986-12-17 | — | — | EP | claimed |
| EP-0090203-B1 | PROCESS FOR PREPARING P.CHLOROPHENOXYACETYL-PIPERONYLPIPERAZINE | RAVIZZA S.p.A. (IT) | 1986-11-12 | — | — | EP | claimed |
| EP-0081425-B1 | PHARMACEUTICAL COMPOSITIONS HAVING NORMOLIPEMIC PROPERTIES AND CONTAINING COMPOUNDS OF THE N-SUBSTITUTED BENZENESULFONAMIDE TYPE | CHOAY S.A. (FR) | 1985-09-18 | — | — | EP | claimed |
| EP-0124067-A1 | 2-(Aminoalkyl)-pyrrole derivatives, process for their manufacture and their use | CASSELLA Aktiengesellschaft (DE) | 1984-11-07 | — | — | EP | claimed |
| US-4178445-A | 7-(α-Substituted glycinamido)-3-substituted methyl-3-cephem-4-carboxylic acids and their derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-12-11 | — | — | US | claimed |
| US-4072703-A | HUMAN AND VETERINARY MEDICINE | CHIMIE & BIOLOGIE (FR) | 1978-02-07 | — | — | US | claimed |
| US-4006163-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1977-02-01 | — | — | US | claimed |
| US-3975532-A | ANALGESIC | ICI UNITED STATES INC. (US) | 1976-08-17 | — | — | US | claimed |
| US-3972774-A | BY AN ESTERASE ENZYME FROM BACILLUS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206809-A1 | PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY | AGO2, TARBP1, TPR | ALDH1A1 4394/4885MEN1 2159/4885RAB9A 4005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.