Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.51 |
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 6/20 | 0.45 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.45 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.45 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.45 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.45 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.45 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.45 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.45 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836670 | 0.80 | MAOA (0.59) | ESR2ESR1MAOAMGAMGAA | |
| SCHEMBL10534569 | 0.77 | LMNA (0.44) | GAA | |
| SCHEMBL9836863 | 0.74 | MAOA (0.64) | ESR2ESR1MAOAMGAMGAA | |
| SCHEMBL5951377 | 0.72 | ESR2 (0.50) | ESR2ESR1MAOAMGAMGAA | |
| SCHEMBL9837184 | 0.70 | ESR1 (0.52) | ESR2ESR1MAOAATP1A1ATP1B1 | |
| SCHEMBL9835772 | 0.70 | ESR2 (0.54) | ESR2ESR1MAOAEGFRGAA | |
| SCHEMBL9836158 | 0.70 | MEN1 (0.58) | ESR2ESR1MAOAGAA | |
| SCHEMBL9836775 | 0.70 | MEN1 (0.42) | ESR2ESR1MAOAEGFRGAA | |
| SCHEMBL9282004 | 0.69 | MAOA (0.63) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL9837177 | 0.68 | PTPN1 (0.48) | ESR2ESR1MAOAEGFRMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175376-B1 | XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4816479-A | HYPOTENSIVE AGENTS, DIURETICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-28 | — | — | US | disclosed |
| US-4661607-A | ANTIEDEMIC AGENTS, HYPOTENSIVE AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0175376-A2 | Xanthone derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-03-26 | — | — | EP | disclosed |