Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 4/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.38 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837295 | 0.69 | CA2 (0.38) | LSSCA2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22193385 | 0.68 | PRSS1 (0.52) | CA2MEN1KMT2A | |
| SCHEMBL6796625 | 0.67 | ADORA2B (0.48) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21318232 | 0.67 | SMN1; SMN2 (0.57) | CA2NPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9837292 | 0.66 | ADORA2B (0.46) | ADORA2AADORA2BCA2ADORA3SMN1; SMN2 | |
| SCHEMBL5970029 | 0.66 | ABL1 (0.43) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27365841 | 0.66 | CA2 (0.48) | LSSCA2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9837043 | 0.66 | KMT2A (0.65) | GAASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL5067508 | 0.62 | LOXL2 (0.61) | LSSCA2NPC1GAASMN1; SMN2 | |
| SCHEMBL6231216 | 0.62 | HRH3 (0.49) | LSSSMN1; SMN2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454773-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | Bundgaard, Hans (DK) | 1991-11-06 | — | — | EP | disclosed |