Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 8/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260246 | 0.72 | ADORA2B (0.62) | ADORA2BADORA3ADORA1ADORA2A | |
| SCHEMBL9837295 | 0.71 | CA2 (0.38) | CA2TP53MAPTSMN1; SMN2 | |
| SCHEMBL22193385 | 0.70 | PRSS1 (0.52) | CA2MAPT | |
| SCHEMBL21318232 | 0.69 | SMN1; SMN2 (0.57) | CA2MAPTSMN1; SMN2 | |
| SCHEMBL27365841 | 0.68 | CA2 (0.48) | CA2TP53MAPTSMN1; SMN2 | |
| SCHEMBL9837043 | 0.67 | KMT2A (0.65) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL9837288 | 0.66 | ADORA2A (0.38) | ADORA2BCA2ADORA3TP53ADORA2A | |
| SCHEMBL18229579 | 0.65 | MMP2 (0.61) | SMN1; SMN2 | |
| SCHEMBL5970338 | 0.64 | ADORA2B (0.56) | ADORA2BADORA2AMAPT | |
| SCHEMBL5067508 | 0.64 | LOXL2 (0.61) | CA2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454773-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | Bundgaard, Hans (DK) | 1991-11-06 | — | — | EP | disclosed |