Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | HPN | P05981 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837292 | 0.71 | ADORA2B (0.46) | CA2TP53MAPTSMN1; SMN2 | |
| SCHEMBL22193385 | 0.69 | PRSS1 (0.52) | CA2ALDH1A1KMT2AMEN1SLC6A2 | |
| SCHEMBL9837288 | 0.69 | ADORA2A (0.38) | CA2KMT2AMEN1LSSTP53 | |
| SCHEMBL21318232 | 0.67 | SMN1; SMN2 (0.57) | CA2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL27365841 | 0.67 | CA2 (0.48) | CA2ALDH1A1KMT2AMEN1LSS | |
| SCHEMBL6796630 | 0.66 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1XDHHCAR1 | |
| SCHEMBL9837043 | 0.64 | KMT2A (0.65) | ALDH1A1KMT2AMEN1TP53MAPT | |
| SCHEMBL6231216 | 0.60 | HRH3 (0.49) | ALDH1A1KMT2AMEN1LSSSMN1; SMN2 | |
| SCHEMBL5067508 | 0.60 | LOXL2 (0.61) | CA2ALDH1A1KMT2AMEN1LSS | |
| SCHEMBL12154217 | 0.59 | ALDH1A1 (0.57) | ALDH1A1KMT2ATP53MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454773-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | Bundgaard, Hans (DK) | 1991-11-06 | — | — | EP | disclosed |