Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 13/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842205 | 0.91 | OPRD1 (0.43) | OPRD1OPRM1SLC6A9OPRK1 | |
| SCHEMBL9842117 | 0.90 | OPRD1 (0.36) | OPRD1OPRM1SLC6A9CACNA2D1CACNA1B | |
| SCHEMBL9842315 | 0.84 | OPRD1 (0.41) | OPRD1OPRM1SLC6A9OPRK1 | |
| SCHEMBL9842323 | 0.84 | OPRD1 (0.35) | OPRD1OPRM1SLC6A9CACNA2D1CACNA1B | |
| SCHEMBL9842022 | 0.73 | SIGMAR1 (0.41) | — | |
| SCHEMBL9842276 | 0.71 | MITF (0.47) | OPRD1 | |
| SCHEMBL8051571 | 0.70 | MEN1 (0.47) | OPRD1OPRM1 | |
| SCHEMBL9842330 | 0.70 | OPRD1 (0.42) | OPRD1OPRM1OPRK1 | |
| SCHEMBL9842111 | 0.70 | OPRD1 (0.40) | OPRD1OPRM1 | |
| SCHEMBL25918370 | 0.69 | SLC6A2 (0.38) | OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461264-A1 | ETHYNYLPHENYL DERIVATIVE, PRODUCTION THEREOF, AND REMEDY FOR DISEASES OF CIRCULATORY ORGANS CONTAINING THE SAME AS ACTIVE INGREDIENT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |