Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6632393 | 0.79 | TMPRSS15 (0.55) | TMPRSS15RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9844093 | 0.77 | TMPRSS15 (0.47) | TMPRSS15RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL27361867 | 0.77 | RAB9A (0.49) | TMPRSS15RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL875579 | 0.77 | TMPRSS15 (0.49) | TMPRSS15RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8305554 | 0.75 | TMPRSS15 (0.48) | TMPRSS15RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL19520914 | 0.72 | TMPRSS15 (0.49) | TMPRSS15RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL27952188 | 0.71 | TMPRSS15 (0.45) | TMPRSS15RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9531781 | 0.69 | NPC1 (0.48) | TMPRSS15RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10200350 | 0.69 | TRPM8 (0.45) | TMPRSS15RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL22660992 | 0.68 | PIK3CD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230126157-A1 | MIRNA-485 INHIBITOR FOR GENE UPREGULATION | BIORCHESTRA CO., LTD. (KR) | 2023-04-27 | — | — | US | disclosed |
| CN-115666655-A | Designer extracellular vesicles for treatment of excitotoxicity | 俄亥俄州立创新基金会 | 2023-01-31 | — | — | CN | disclosed |
| EP-4100067-A1 | MIRNA-485 INHIBITOR FOR GENE UPREGULATION | Biorchestra Co., Ltd. (KR) | 2022-12-14 | — | — | EP | disclosed |
| WO-2022003609-A1 | SNP DIAGNOSTIC METHODS | BIORCHESTRA CO., LTD. (KR) | 2022-01-06 | — | — | WO | disclosed |
| WO-2021156831-A1 | MIRNA-485 INHIBITOR FOR GENE UPREGULATION | BIORCHESTRA CO., LTD. (KR) | 2021-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230126157-A1 | MIRNA-485 INHIBITOR FOR GENE UPREGULATION | NRP1, SORT1, NR4A3 | TMPRSS15 3188/4885RAB9A 2284/4885NPC1 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.