Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846762 | 0.88 | OPRM1 (0.33) | OPRM1OPRD1OPRK1 | |
| SCHEMBL9846679 | 0.84 | SIGMAR1 (0.33) | ADRA1A | |
| SCHEMBL9846738 | 0.81 | LMNA (0.33) | IDH1HTR7KCNK2ADRB2CHRM2 | |
| SCHEMBL9846720 | 0.73 | PBRM1 (0.37) | HTR2AHTR2CCTSDBACE1LMNA | |
| SCHEMBL9846796 | 0.71 | AHR (0.33) | SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9846798 | 0.70 | PDE4A (0.39) | HTR2APDE4DCTSDBACE1LMNA | |
| SCHEMBL9846701 | 0.69 | ATM (0.33) | ADRA1AHRH4CTSDBACE1 | |
| SCHEMBL9846715 | 0.65 | CTSD (0.36) | IDH1HTR7KCNK2ADRB2CHRM2 | |
| SCHEMBL9846748 | 0.64 | TSHR (0.38) | CYP1A2CYP3A4CYP2D6CYP2C9SMN1; SMN2 | |
| SCHEMBL25269677 | 0.63 | HDAC6 (0.46) | MEN1KMT2ABLMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450487-A1 | Benzoxazine derivatives, method for their preparation and their use for treating or prophylaxis of diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |