Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 3/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846679 | 0.84 | SIGMAR1 (0.33) | ATMSIGMAR1PER2ADRA1DADRA1A | |
| SCHEMBL9846720 | 0.83 | PBRM1 (0.37) | BACE1CTSD | |
| SCHEMBL9846780 | 0.77 | PDK2 (0.39) | HDAC4HDAC8 | |
| SCHEMBL9846762 | 0.70 | OPRM1 (0.33) | — | |
| SCHEMBL9372567 | 0.69 | ADK (0.32) | ATMSIGMAR1HRH4 | |
| SCHEMBL9846735 | 0.69 | IDH1 (0.33) | BACE1CTSDADRA1AHRH4 | |
| SCHEMBL9846707 | 0.69 | ACHE (0.35) | — | |
| SCHEMBL9373066 | 0.67 | ADK (0.33) | — | |
| SCHEMBL13194218 | 0.65 | BACE1 (0.48) | BACE1 | |
| SCHEMBL266004 | 0.65 | MEN1 (0.50) | SIGMAR1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450487-A1 | Benzoxazine derivatives, method for their preparation and their use for treating or prophylaxis of diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |