SCHEMBL9847567

SCHEMBL9847567

COC1CCc2ccc(Oc3ccc(N=C=O)cc3)cc2O1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.35
PPARA Q07869 2/20 0.35
PPARD Q03181 1/20 0.35
CA2 P00918 3/20 0.32
CA5A P35218 1/20 0.32
FFAR1 O14842 2/20 0.32
FAAH O00519 2/20 0.31
HTR1A P08908 1/20 0.31
HTR1D P28221 1/20 0.31
MTNR1B P49286 1/20 0.30
CA1 P00915 2/20 0.30
ACHE P22303 2/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847598 0.88 PPARG (0.37) PPARGPPARAPPARDFFAR1MTNR1B
SCHEMBL9847659 0.80 ALDH1A1 (0.46) PPARGPPARAPPARD
SCHEMBL6505490 0.77 CA2 (0.48) CA2CA5AFFAR1HTR1AHTR1D
SCHEMBL9847595 0.74 MCHR1 (0.42) PPARGPPARAPPARDMTNR1B
SCHEMBL9749254 0.74 PPARG (0.39) PPARGPPARAPPARD
SCHEMBL9847558 0.74 PPARA (0.38) PPARGPPARAPPARDCA2CA5A
SCHEMBL9847529 0.73 MEN1 (0.43) PPARGPPARAPPARDCA2MTNR1B
SCHEMBL9847571 0.71 PPARG (0.42) PPARGPPARAPPARD
SCHEMBL9847591 0.70 HIF1A (0.33)
SCHEMBL9847583 0.70 PPARA (0.40) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434074-A2 Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-06-26 EP disclosed