Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504118 | 0.81 | LMNA (0.58) | LMNAKMT2ALPAR1 | |
| SCHEMBL13284155 | 0.78 | ALDH1A1 (0.45) | LMNAKMT2A | |
| SCHEMBL462304 | 0.75 | LPAR1 (0.66) | LMNAKMT2ALPAR1 | |
| SCHEMBL9723518 | 0.75 | LMNA (0.54) | LMNAKMT2ALPAR1 | |
| SCHEMBL9504026 | 0.75 | SOAT2 (0.57) | — | |
| SCHEMBL8321568 | 0.73 | — | — | |
| SCHEMBL9435674 | 0.73 | KMT2A (0.63) | LMNAKMT2ALPAR1 | |
| SCHEMBL15716728 | 0.73 | CTSS (0.51) | KMT2A | |
| SCHEMBL14065364 | 0.73 | ALDH1A1 (0.53) | KMT2A | |
| SCHEMBL7598651 | 0.72 | TSHR (0.47) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |