Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.54 |
| ▸ | CTSS | P25774 | 7/20 | 0.54 |
| ▸ | CTSL | P07711 | 6/20 | 0.54 |
| ▸ | CTSB | P07858 | 6/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | KYNU | Q16719 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149388 | 0.93 | KYNU (0.58) | CTSKCTSSCTSLCTSBCASP1 | |
| SCHEMBL14677202 | 0.91 | CTSK (0.56) | CTSKCTSSCTSLCTSBCASP1 | |
| SCHEMBL15381003 | 0.91 | ALDH1A1 (0.56) | CTSKCTSSCTSLCTSBCASP1 | |
| SCHEMBL25717532 | 0.89 | PPARA (0.54) | CTSKCTSSCTSLCTSBTACR1 | |
| SCHEMBL7414045 | 0.87 | CTSK (0.51) | CTSKCTSSCTSLCTSBCASP1 | |
| SCHEMBL19227539 | 0.85 | ALDH1A1 (0.57) | CTSKCTSSCTSLCTSBCASP1 | |
| SCHEMBL4280674 | 0.84 | CASP1 (0.67) | CASP1 | |
| SCHEMBL4280669 | 0.84 | CASP1 (0.67) | CASP1 | |
| SCHEMBL9312398 | 0.83 | CASP1 (0.60) | CTSKCTSSCTSLCTSBCASP1 | |
| SCHEMBL8765627 | 0.83 | CASP1 (0.60) | CTSKCTSSCTSLCTSBCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |