Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | NMT1 | P30419 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849431 | 0.76 | MAOA (0.56) | ALDH1A1CYP19A1NMT1SMN1; SMN2POLB | |
| SCHEMBL5093896 | 0.76 | TBXAS1 (0.53) | ALDH1A1CYP19A1TBXAS1SMN1; SMN2NPC1 | |
| SCHEMBL9849398 | 0.76 | L3MBTL1 (0.55) | ALDH1A1CYP19A1TBXAS1NMT1SMN1; SMN2 | |
| SCHEMBL1937770 | 0.75 | HCAR3 (0.57) | SMN1; SMN2 | |
| Maleic Acid SCHEMBL9849513 | 0.75 | NMT1 (0.46) | ALDH1A1CYP19A1TBXAS1NMT1SMN1; SMN2 | |
| SCHEMBL1680894 | 0.74 | HCAR3 (0.76) | — | |
| SCHEMBL4418348 | 0.74 | KDM4E (0.56) | ALDH1A1SMN1; SMN2GAATSHR | |
| SCHEMBL13450232 | 0.74 | ALDH1A1 (0.75) | ALDH1A1CYP19A1SMN1; SMN2NPC1POLB | |
| SCHEMBL6302832 | 0.74 | TBXAS1 (0.87) | TBXAS1GAAQPCT | |
| SCHEMBL5205802 | 0.73 | NNMT (0.60) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |