Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982672 | 0.84 | GAA (0.47) | CYP1A2CYP2A6RAB9ALMNATNF | |
| SCHEMBL3299248 | 0.80 | PYCR1 (0.47) | CYP1A2CYP2A6RAB9ALMNASMN1; SMN2 | |
| SCHEMBL11323610 | 0.79 | TAAR1 (0.43) | RAB9ALMNASMN1; SMN2HTTTNF | |
| SCHEMBL3301748 | 0.78 | CYP3A4 (0.53) | RAB9ALMNASMN1; SMN2HTTTNF | |
| SCHEMBL28262947 | 0.77 | CYP2A6 (0.43) | CYP1A2CYP2A6RAB9ALMNASMN1; SMN2 | |
| SCHEMBL6546220 | 0.76 | RAB9A (0.44) | RAB9ALMNASMN1; SMN2HTTTNF | |
| SCHEMBL9451516 | 0.74 | — | — | |
| SCHEMBL11194149 | 0.73 | LMNA (0.48) | RAB9ALMNASMN1; SMN2HTTTNF | |
| SCHEMBL7460688 | 0.73 | HSPA5 (0.59) | CYP1A2RAB9ASMN1; SMN2HTTNPC1 | |
| SCHEMBL21323294 | 0.73 | HTT (0.46) | RAB9ALMNASMN1; SMN2HTTTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786885-B1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | MERCK PATENT GMBH (DE) | 2011-05-18 | — | — | EP | claimed |
| US-20080113215-A1 | Electroluminescent Materials and Devices | MERCK PATENT GMBH (DE) | 2008-05-15 | — | — | US | claimed |
| US-20070252108-A1 | Electroluminescent Materials and Devices | MERCK PATENT GMBH (DE) | 2007-11-01 | — | — | US | claimed |
| EP-2984079-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2020-07-01 | — | — | EP | disclosed |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | POWER OLEDS LIMITED (GB) | 2019-10-08 | — | — | US | disclosed |
| US-20180323378-A9 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LIMITED (GB) | 2018-11-08 | — | — | US | disclosed |
| EP-2232611-B1 | BARRIER COATED SUBSTRATE AND ELECTRO-OPTICAL DEVICE | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-9437828-B2 | Electroluminescent device using azomethine-lithium-complex as electron injection layer | MERCK PATENT GMBH (DE) | 2016-09-06 | — | — | US | disclosed |
| EP-2984079-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | Power Oleds Limited (GB) | 2016-02-17 | — | — | EP | disclosed |
| US-20160035983-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2016-02-04 | — | — | US | disclosed |
| US-9221770-B2 | Compounds having electron transport properties, their preparation and use | MERCK PATENT GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| WO-2009090423-A1 | BARRIER COATED SUBSTRATE AND ELECTRO-OPTICAL DEVICE | MERCK PATENT GMBH (DE) | 2009-07-23 | — | — | WO | disclosed |
| US-20090167158-A1 | Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
| WO-2008081178-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008078114-A1 | ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008078115-A1 | PHENANTHROLINE COMPOUNDS AND ELECTROLUMINESCENT DEVICES USING THE SAME | MERCK PATENT GMBH (DE) | 2008-07-03 | — | — | WO | disclosed |
| US-20080113215-A1 | Electroluminescent Materials and Devices | MERCK PATENT GMBH (DE) | 2008-05-15 | — | — | US | disclosed |
| US-20070252108-A1 | Electroluminescent Materials and Devices | MERCK PATENT GMBH (DE) | 2007-11-01 | — | — | US | disclosed |
| EP-1786885-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | OLED-T LIMITED (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006016176-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | OLED-T LIMITED (GB) | 2006-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180323378-A9 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | NAT1, SLCO2A1, SLCO2B1 | CYP1A2 296/4885CYP2A6 1385/4885RAB9A 913/4885 |
| US-20070252108-A1 | Electroluminescent Materials and Devices | AAAS, ANXA1, ANXA2 | CYP1A2 1707/4885CYP2A6 3902/4885RAB9A 690/4885 |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | NAT1, SLCO2A1, SLCO2B1 | CYP1A2 296/4885CYP2A6 1385/4885RAB9A 913/4885 |
| US-20080113215-A1 | Electroluminescent Materials and Devices | AAAS, ACMSD, KCNH1 | CYP1A2 1148/4885CYP2A6 3257/4885RAB9A 1205/4885 |
| US-20160035983-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | NAT1, SLCO2A1, SLCO2B1 | CYP1A2 296/4885CYP2A6 1385/4885RAB9A 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.