Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.45 |
| ▸ | LMNA | P02545 | 13/20 | 0.45 |
| ▸ | HTT | P42858 | 11/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856024 | 0.86 | LMNA (0.44) | MAPTLMNAHTTALOX12MEN1 | |
| SCHEMBL9855981 | 0.84 | MAPT (0.40) | MAPTLMNAHTTALOX12MEN1 | |
| SCHEMBL9856153 | 0.82 | LMNA (0.41) | MAPTLMNAHTTALOX12MEN1 | |
| SCHEMBL9856021 | 0.79 | MTNR1A (0.44) | LMNAHTTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9856226 | 0.76 | MTNR1A (0.44) | LMNAHTTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL9856338 | 0.75 | MAPT (0.48) | MAPTLMNAHTTALOX12MEN1 | |
| SCHEMBL9856284 | 0.74 | CA2 (0.43) | MAPTLMNAHTTALOX12MEN1 | |
| SCHEMBL9856352 | 0.71 | MAOA (0.42) | LMNAHPGD | |
| SCHEMBL10394300 | 0.69 | SLC6A4 (0.50) | HTTHPGD | |
| SCHEMBL9855896 | 0.69 | L3MBTL1 (0.41) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |