Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL9856782 | 0.74 | TP53 (0.44) | HPGDPPARGPPARACTSSCTSK | |
| SCHEMBL9856989 | 0.68 | SLC6A2 (0.46) | PPARGSLC6A2SLC6A4POLBALDH1A1 | |
| SCHEMBL8502073 | 0.67 | LMNA (0.41) | HPGDSLC6A2SLC6A4ALDH1A1KMT2A | |
| SCHEMBL23189271 | 0.67 | APAF1 (0.51) | HPGDPPARGPPARACTSSCTSK | |
| SCHEMBL31558898 | 0.67 | APAF1 (0.51) | HPGDPPARGPPARACTSSCTSK | |
| SCHEMBL1452939 | 0.67 | APAF1 (0.51) | HPGDPPARGPPARACTSSCTSK | |
| SCHEMBL10595053 | 0.65 | CTSB (0.44) | HPGDPPARGPPARAALDH1A1KMT2A | |
| SCHEMBL5297379 | 0.65 | LMNA (0.43) | HPGDSLC6A2SLC6A4POLBALDH1A1 | |
| SCHEMBL8437061 | 0.65 | EPHX2 (0.49) | HPGDPPARGPPARACTSSCTSK | |
| Hydrochloric Acid SCHEMBL28479104 | 0.65 | CTSS (0.46) | HPGDPPARGPPARACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0318233-A2 | Improvements in or relating to serotonin and norepinephrine uptake inhibitors | ELI LILLY AND COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |