Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15470773 | 0.87 | SLC7A5 (0.41) | RXRARXRBALDH1A1PTGS2PLK1 | |
| SCHEMBL28288053 | 0.83 | GAA (0.45) | RXRARXRBALDH1A1GAAMAPT | |
| SCHEMBL11755705 | 0.80 | PTGS2 (0.51) | RXRARXRBALDH1A1PTGS2PLK1 | |
| SCHEMBL7937910 | 0.79 | GPR84 (0.52) | ALDH1A1PTGS2PLK1CNR2 | |
| SCHEMBL3890873 | 0.79 | CNR2 (0.51) | ALDH1A1PTGS2BCL2MAPTCNR2 | |
| SCHEMBL10498757 | 0.78 | RXRA (0.48) | RXRARXRBALDH1A1PTGS2PLK1 | |
| SCHEMBL334347 | 0.78 | RXRA (0.64) | RXRARXRBALDH1A1PTGS2BCL2 | |
| SCHEMBL526436 | 0.76 | ALDH1A1 (0.64) | RXRARXRBALDH1A1PLK1GAA | |
| SCHEMBL1004651 | 0.76 | RXRA (0.47) | RXRARXRBALDH1A1PTGS2PLK1 | |
| SCHEMBL31490509 | 0.76 | CES2 (0.38) | ALDH1A1GLRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014824-B | Application of heterocyclic compound | 上海科技大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114014824-A | Application of heterocyclic compound | 上海科技大学 | 2022-02-08 | — | — | CN | disclosed |
| US-7875631-B2 | e.g.1-(3,5-dichlorophenyl)-2-formyl-6-methoxy-1,2,3,4-tetrahydroisoquinoline; to prevent and/or treat cancer and other abnormal cell growth, and metabolic as well as blood vessel proliferate disorders, in which uncontrolled expression of insulin-like growth factor-1 receptor is observed | ANALYTECON S.A. (CH) | 2011-01-25 | — | — | US | disclosed |
| EP-0945764-B1 | Photoresist composition | SUMITOMO CHEMICAL CO (JP) | 2003-06-18 | — | — | EP | disclosed |
| EP-0945764-A2 | Photoresist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |