Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696260 | 0.85 | SERPINE1 (0.43) | PTGDR2ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL30524282 | 0.85 | SERPINE1 (0.43) | PTGDR2ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL9881101 | 0.80 | ALDH1A1 (0.42) | PTGDR2ALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL297205 | 0.75 | CA1 (0.56) | ALDH1A1SMN1; SMN2HTTHSD17B10MAPT | |
| SCHEMBL2137125 | 0.74 | FABP7 (0.39) | ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL19399153 | 0.73 | THRA (0.33) | PTGDR2ALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL695666 | 0.72 | PTK2B (0.50) | ALDH1A1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL27601473 | 0.72 | GAA (0.50) | ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL28829588 | 0.72 | CXCL8 (0.42) | PTGDR2HTTMAPTKMT2ATP53 | |
| SCHEMBL1977066 | 0.71 | ALDH1A1 (0.48) | ALDH1A1HPGDSMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410929-A2 | Linear polymers | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | disclosed |