Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PNMT | P11086 | 2/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865863 | 0.79 | PKM (0.36) | KDM4EUSP7GRIA4HSD17B10 | |
| SCHEMBL9864602 | 0.72 | KEAP1 (0.35) | KEAP1NFE2L2USP7GRIA4 | |
| SCHEMBL9865123 | 0.72 | KEAP1 (0.35) | KEAP1NFE2L2USP7GRIA4 | |
| SCHEMBL9864443 | 0.72 | USP7 (0.57) | KEAP1NFE2L2KDM4EUSP7GRIA4 | |
| SCHEMBL741497 | 0.72 | KEAP1 (0.71) | KEAP1NFE2L2KDM4EUSP7GRIA4 | |
| SCHEMBL10738993 | 0.71 | VCAM1 (0.39) | USP7GRIA4 | |
| SCHEMBL6928589 | 0.69 | KEAP1 (0.53) | KEAP1NFE2L2KDM4EUSP7 | |
| SCHEMBL1998846 | 0.69 | PNMT (0.33) | PNMT | |
| SCHEMBL10532548 | 0.67 | PNMT (0.32) | KDM4EPNMTHSD17B10 | |
| SCHEMBL742310 | 0.66 | L3MBTL1 (0.50) | KEAP1NFE2L2KDM4EUSP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |