Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867797 | 0.89 | MEN1 (0.33) | MEN1KMT2AHTR7CYP1A2CYP2C19 | |
| SCHEMBL10373802 | 0.87 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9866531 | 0.84 | POLB (0.36) | HTR7HCAR1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9869258 | 0.83 | NFE2L2 (0.33) | NFE2L2 | |
| SCHEMBL9865807 | 0.82 | NAAA (0.34) | HTR7NFE2L2 | |
| SCHEMBL9866719 | 0.81 | L3MBTL1 (0.38) | MEN1KMT2AVCAM1ALDH1A1TSHR | |
| SCHEMBL9866727 | 0.81 | NFE2L2 (0.34) | MEN1KMT2AHCAR1NFE2L2CYP1A2 | |
| SCHEMBL9865651 | 0.81 | HCAR1 (0.33) | HCAR1NFE2L2ALDH1A1 | |
| SCHEMBL9867762 | 0.79 | ALDH1A1 (0.37) | HCAR1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9866386 | 0.78 | MEN1 (0.43) | MEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| CN-1042144-A | Pesticidal compound | ICI PLC (GB) | 1990-05-16 | — | — | CN | disclosed |